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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
9.09
Human Site:
Y566
Identified Species:
20
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
Y566
F
N
L
P
A
S
H
Y
Y
K
Y
K
Q
Q
F
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
Y542
F
N
L
P
A
S
H
Y
Y
K
Y
K
Q
Q
F
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
N474
E
V
E
P
T
S
E
N
E
E
V
H
D
E
A
Dog
Lupus familis
XP_853953
898
99758
R544
P
D
A
A
D
S
T
R
L
E
H
Q
P
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
Y576
F
N
L
P
A
S
H
Y
Y
K
Y
K
Q
Q
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
R475
S
S
S
S
S
E
D
R
N
R
M
K
T
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
F557
S
N
L
T
A
S
H
F
Y
K
Y
K
Q
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
K451
R
S
A
D
E
S
N
K
N
L
L
L
R
D
A
Honey Bee
Apis mellifera
XP_393005
895
100160
N524
H
F
P
D
V
V
L
N
E
K
G
V
T
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
A490
G
G
E
N
D
A
L
A
E
N
G
G
G
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
100
N.A.
N.A.
0
6.6
N.A.
80
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
26.6
40
N.A.
100
N.A.
N.A.
0
26.6
N.A.
86.6
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
37
10
0
10
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
19
19
0
10
0
0
0
0
0
10
10
0
% D
% Glu:
10
0
19
0
10
10
10
0
28
19
0
0
0
10
10
% E
% Phe:
28
10
0
0
0
0
0
10
0
0
0
0
0
0
37
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
19
10
10
0
10
% G
% His:
10
0
0
0
0
0
37
0
0
0
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
46
0
46
0
10
0
% K
% Leu:
0
0
37
0
0
0
19
0
10
10
10
10
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
37
0
10
0
0
10
19
19
10
0
0
0
0
0
% N
% Pro:
10
0
10
37
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
37
37
0
% Q
% Arg:
10
0
0
0
0
0
0
19
0
10
0
0
10
0
0
% R
% Ser:
19
19
10
10
10
64
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
10
10
0
10
0
0
0
0
0
19
0
10
% T
% Val:
0
10
0
0
10
10
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
37
0
37
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _